Interventions
Start with the foundations. Then explore the frontier.
Healthy longevity is bigger than a supplement stack. Use familiar foundations to calibrate the evidence for medicines, supplements and experimental geroscience.
Experimental & emerging geroscience
Compounds and therapies already tracked
The original evidence catalog remains intact, including human trials, result interpretation, safety and a separate animal/lab evidence layer.
Experimental geroprotector
17alpha-estradiol
Automated longevity evidence pipeline intervention.
Early-stage human evidence
- Human research
- Results
- Safety
Drug / geroscience
Acarbose
Automated longevity evidence pipeline intervention.
1 healthy-aging outcome area tracked
- Human research
- Results
- Safety
Longevity compound
Alpha-ketoglutarate (AKG)
Automated longevity evidence pipeline intervention.
Human research is being tracked
- Human research
- Results
- Safety
Longevity compound
Berberine
Automated longevity evidence pipeline intervention.
Early-stage human evidence
- Human research
- Results
- Safety
Senolytic candidate
Dasatinib + Quercetin
Automated longevity evidence pipeline intervention.
4 healthy-aging outcome areas tracked
- Human research
- Results
- Safety
Longevity peptide
Epitalon / Epithalon
Automated longevity evidence pipeline intervention.
Early-stage human evidence
- Human research
- Results
- Safety
Senolytic candidate
Fisetin
Automated longevity evidence pipeline intervention.
1 healthy-aging outcome area tracked
- Human research
- Results
- Safety
Longevity compound
GlyNAC
Automated longevity evidence pipeline intervention.
Early-stage human evidence
- Human research
- Results
- Safety
Drug / geroscience
Lithium
Automated longevity evidence pipeline intervention.
4 healthy-aging outcome areas tracked
- Human research
- Results
- Safety
Drug / geroscience
Metformin
Automated longevity evidence pipeline intervention.
7 healthy-aging outcome areas tracked
- Human research
- Results
- Safety
Longevity compound
NAD+
Automated longevity evidence pipeline intervention.
6 healthy-aging outcome areas tracked
- Human research
- Results
- Safety
Longevity compound
Nicotinamide riboside (NR)
Automated longevity evidence pipeline intervention.
5 healthy-aging outcome areas tracked
- Human research
- Results
- Safety
Longevity compound
NMN
Automated longevity evidence pipeline intervention.
Human research is being tracked
- Human research
- Results
- Safety
Longevity compound
Pterostilbene
Automated longevity evidence pipeline intervention.
Human research is being tracked
- Human research
- Results
- Safety
Senolytic candidate
Quercetin
Automated longevity evidence pipeline intervention.
4 healthy-aging outcome areas tracked
- Human research
- Results
- Safety
Drug / geroscience
Rapamycin (sirolimus)
mTOR inhibitor being studied for effects on aging biology and healthspan-related outcomes.
1 healthy-aging outcome area tracked
- Human research
- Results
- Safety
Longevity compound
Resveratrol
Automated longevity evidence pipeline intervention.
5 healthy-aging outcome areas tracked
- Human research
- Results
- Safety
Longevity compound
Spermidine
Automated longevity evidence pipeline intervention.
Human research is being tracked
- Human research
- Results
- Safety
Longevity compound
Taurine
Automated longevity evidence pipeline intervention.
1 healthy-aging outcome area tracked
- Human research
- Results
- Safety
Longevity compound
Urolithin A
Automated longevity evidence pipeline intervention.
Human research is being tracked
- Human research
- Results
- Safety
Evidence maturity is not a benefit ranking. Population, outcome and study design matter. How we interpret evidence.