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Longevity compound

Taurine

Automated longevity evidence pipeline intervention.

Where the science stands

This page summarizes the current human evidence captured in the Longevity Compass database. Result interpretation is conservative and unresolved outcomes remain unknown.

Evidence depth 61 / 100

Research path

From biological idea to human evidence

These stages show different kinds of evidence for Taurine. Moving through them does not mean an intervention is proven to slow aging.

  1. 1

    Biological idea

    Reviewing animal and laboratory research…

  2. 2

    Human testing

    2 direct aging trial links and 10 related trial links tracked. A trial count describes research activity, not benefit.

  3. 3

    What results show

    0 beneficial, 0 neutral and 0 harmful result links interpreted; 0 remain unresolved.

  4. 4

    Still unanswered

    Whether these findings translate into meaningful, lasting healthy-aging benefits in people remains unproven. Longer follow-up and clearer safety and clinical outcomes are needed.

How AgeBeacon evaluates evidence →

Beyond human trials

The bigger longevity story

Loading animal and laboratory evidence…

Animal and cell studies help explain biological plausibility and identify promising directions. They are shown separately and do not increase the human evidence-depth score.

Signals we're watching

What human studies are measuring

Cognition

2 result(s) are linked, but direction remains unknown.

Research depth

Human evidence picture

Evidence depth describes how much relevant human research exists; it is not an efficacy score. Unknown results are not treated as neutral.

2
Direct aging trials
10
Indirect relevant trials
34
Publications linked
2
Results publications

Interpreted results

Beneficial
0
Neutral
0
Harmful
0
Unknown / unresolved
0

Population relevance

Healthy / aging
2
Disease-specific
1

Safety evidence

0

Trials currently identified with safety-result data.

Go to the source

Studies & publications

Inspect the original evidence behind this profile. Links open the trial registry, PubMed or the publication DOI.

The Effects of a Dietary Supplement on Exercise Performance in Healthy Older Adults"NCT01073332INTERVENTIONAL · NA · 16 participants · COMPLETEDEffects Of Daily Taurine Intake For 6 Months On Biological Age and Body Metabolism Indicators As Well As Physical Fitness In 55-75-year-old Women And MenNCT06613542INTERVENTIONAL · NA · 90 participants · COMPLETEDTaurine Supplementation on Cognitive Function in Patients With DiabetesNCT03410173INTERVENTIONAL · NA · 200 participants · UNKNOWNTaurine as a Possible Anti-aging Therapy?NCT05149716INTERVENTIONAL · NA · 24 participants · COMPLETEDNear-Infrared Spectroscopy, Acute Taurine Supplementation, and Isolated Muscular Endurance and Fatigue Resistance in Young Healthy AdultsNCT07654946INTERVENTIONAL · NA · 34 participants · RECRUITINGTaurine in Periodontitis and AgingNCT06635369INTERVENTIONAL · NA · 66 participants · COMPLETEDTaurine Supplementation and Training Effects on Energy Metabolism, Inflammation and Oxidative Stress in Obese WomenNCT04279600INTERVENTIONAL · NA · 24 participants · COMPLETEDMetabolic and Molecular Responses Under the Effect of Taurine Supplementation With and Without Multicomponent TrainingNCT05437952INTERVENTIONAL · NA · 60 participants · UNKNOWNTaurine Supplementation and Exercise on Irisin Levels in ObesityNCT04646512INTERVENTIONAL · NA · 31 participants · COMPLETEDTaurine Supplementation Associated or Not With Exercise: Effect on Browning of White Adipose Tissue in Elderly Women With Sarcopenic ObesityNCT05415176INTERVENTIONAL · NA · 40 participants · UNKNOWNProtein Supplementation Intervention for Improving Muscle Mass and Physical Performance in Older People With SarcopeniaNCT04516421INTERVENTIONAL · NA · 80 participants · UNKNOWNExercise and Taurine Supplementation on Intramuscular Fat in Older Women With ObesityNCT07730255INTERVENTIONAL · NA · 44 participants · ACTIVE_NOT_RECRUITINGSayedyousef H, Yilmaz O, Ozturk C, Demir B, Toygar HU, Balci N. Taurine, Sirtuin-1 and TNF- alpha levels in different aged adults with periodontitis: a pilot study. BMC Oral Health. 2025 Aug 22;25(1):1354. doi: 10.1186/s12903-025-06690-z.PMID 40847336Results publicationDe Carvalho FG, Brandao CFC, Munoz VR, Batitucci G, Tavares MEA, Teixeira GR, Pauli JR, De Moura LP, Ropelle ER, Cintra DE, da Silva ASR, Junqueira-Franco MVM, Marchini JS, De Freitas EC. Taurine supplementation in conjunction with exercise modulated cytokines and improved subcutaneous white adipose tissue plasticity in obese women. Amino Acids. 2021 Sep;53(9):1391-1403. doi: 10.1007/s00726-021-03041-4. Epub 2021 Jul 13.PMID 34255136Results publicationDavis BH, Spielmann G, Johannsen NM, Fairchild V, Allerton TD, Irving BA. Effect of training status on muscle excitation and neuromuscular fatigue with resistance exercise with and without blood flow restriction in young men. Physiol Rep. 2025 Mar;13(6):e70274. doi: 10.14814/phy2.70274.PMID 40110914Linked publicationTripp TR, McDougall RM, Frankish BP, Wiley JP, Lun V, MacInnis MJ. Contraction intensity affects NIRS-derived skeletal muscle oxidative capacity but not its relationships to mitochondrial protein content or aerobic fitness. J Appl Physiol (1985). 2024 Feb 1;136(2):298-312. doi: 10.1152/japplphysiol.00342.2023. Epub 2023 Dec 7.PMID 38059287Linked publicationSumner MD, Beard S, Pryor EK, Das I, McCully KK. Near Infrared Spectroscopy Measurements of Mitochondrial Capacity Using Partial Recovery Curves. Front Physiol. 2020 Feb 14;11:111. doi: 10.3389/fphys.2020.00111. eCollection 2020.PMID 32116804Linked publicationHanna R, Gosalia J, Demalis A, Hobson Z, McCully KK, Irving BA, Mookerjee S, Vairo GL, Proctor DN. Bilateral NIRS measurements of muscle mitochondrial capacity: Feasibility and repeatability. Physiol Rep. 2021 Apr;9(8):e14826. doi: 10.14814/phy2.14826.PMID 33945230Linked publicationRyan TE, Brizendine JT, McCully KK. A comparison of exercise type and intensity on the noninvasive assessment of skeletal muscle mitochondrial function using near-infrared spectroscopy. J Appl Physiol (1985). 2013 Jan 15;114(2):230-7. doi: 10.1152/japplphysiol.01043.2012. Epub 2012 Nov 15.PMID 23154991Linked publicationRyan TE, Erickson ML, Brizendine JT, Young HJ, McCully KK. Noninvasive evaluation of skeletal muscle mitochondrial capacity with near-infrared spectroscopy: correcting for blood volume changes. J Appl Physiol (1985). 2012 Jul;113(2):175-83. doi: 10.1152/japplphysiol.00319.2012. Epub 2012 May 10.PMID 22582211Linked publicationWaldron M, Patterson SD, Tallent J, Jeffries O. The Effects of an Oral Taurine Dose and Supplementation Period on Endurance Exercise Performance in Humans: A Meta-Analysis. Sports Med. 2018 May;48(5):1247-1253. doi: 10.1007/s40279-018-0896-2.PMID 29546641Linked publicationDe Luca A, Pierno S, Camerino DC. Taurine: the appeal of a safe amino acid for skeletal muscle disorders. J Transl Med. 2015 Jul 25;13:243. doi: 10.1186/s12967-015-0610-1.PMID 26208967Linked publicationBostrom P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Bostrom EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, Hojlund K, Gygi SP, Spiegelman BM. A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 2012 Jan 11;481(7382):463-8. doi: 10.1038/nature10777.PMID 22237023Linked publicationGhandforoush-Sattari M, Mashayekhi S, Krishna CV, Thompson JP, Routledge PA. Pharmacokinetics of oral taurine in healthy volunteers. J Amino Acids. 2010;2010:346237. doi: 10.4061/2010/346237. Epub 2010 Jun 29.PMID 22331997Linked publication

The big unanswered question

Can promising biology translate into meaningful healthy-aging benefits?

That is the standard this evidence profile is tracking. New trials and results can strengthen, weaken or change the picture over time.

Confidence: lowScore model: v0.5-curated-ruleUpdated: 2026-09-21Source: live evidence database