Your healthy-aging goal
What improves blood sugar, insulin sensitivity or weight in humans?
Glucose control, insulin sensitivity, lipids and body composition measured in human trials.
Follow the signal, understand the certainty
Some ideas are promising, some are early, and some have disappointed. We show Evidence, Results and Safety separately so you can see both the possibility and the uncertainty — see how we weigh evidence.
Studied without a demonstrated benefit
Human studies have looked at this outcome but the interpreted results shown here have not demonstrated a benefit.
Listed alphabetically — not ranked
Still being studied
The human evidence is too sparse or unresolved to judge this outcome yet.
Listed alphabetically — not ranked
Biomarker — does not establish a health benefit
Drug / geroscience
Lithium
A medicine and naturally occurring element being studied at different exposure levels for effects on cellular signaling, brain health and aging biology.
4 healthy-aging outcome areas tracked
- Human research
10 outcome assessment(s) still require classification.
- Signal · Metabolic health
- Safety
10 outcome assessment(s) still require classification.
1 result(s) are linked, but direction remains unknown.
Biomarker — does not establish a health benefit
Longevity compound
NAD+
A central cellular coenzyme involved in energy metabolism, DNA repair and stress responses, studied because NAD biology changes with age.
6 healthy-aging outcome areas tracked
- Human research
50 outcome assessment(s) still require classification.
- Signal · Metabolic health
- Safety
50 outcome assessment(s) still require classification.
5 result(s) are linked, but direction remains unknown.
Biomarker — does not establish a health benefit
Longevity compound
Resveratrol
A plant polyphenol studied for effects on nutrient sensing, metabolism and cellular stress-response pathways associated with aging.
5 healthy-aging outcome areas tracked
- Human research
17 outcome assessment(s) still require classification.
- Signal · Metabolic health
- Safety
17 outcome assessment(s) still require classification.
5 result(s) are linked, but direction remains unknown.