Urolithin A

Walking performance, muscle endurance and ATP production are different endpoints. Reading the primary comparisons before the secondary findings helps keep the result in proportion.

A change in a laboratory marker, a test score and everyday function are different outcomes. A statistically detectable result does not by itself tell us whether someone would notice a worthwhile difference.

Check the measured endpoint, comparison and study population. The full profile preserves effect estimates and the source's clinical-significance assessment, including when that assessment is not supplied.

The claim to test: A muscle-related signal proves better everyday performance or longer life.

What the reviewed records say:

The gap: Secondary findings do not overturn neutral primary outcomes or prove an effect on healthy lifespan.

Durability, effects in other populations and healthy-lifespan outcomes need their own evidence.

Independent replication, meaningful human outcomes, longer follow-up and better safety reporting would make these results easier to interpret.

Secondary findings do not overturn neutral primary outcomes or prove an effect on healthy lifespan.