Your healthy-aging goal
What actually lowers chronic inflammation in people?
Inflammatory markers such as CRP and IL-6. Lower markers are promising but are biomarkers, not proven health outcomes.
Follow the signal, understand the certainty
Some ideas are promising, some are early, and some have disappointed. We show Evidence, Results and Safety separately so you can see both the possibility and the uncertainty — see how we weigh evidence.
Studied without a demonstrated benefit
Human studies have looked at this outcome but the interpreted results shown here have not demonstrated a benefit.
Listed alphabetically — not ranked
Still being studied
The human evidence is too sparse or unresolved to judge this outcome yet.
Listed alphabetically — not ranked
Biomarker — does not establish a health benefit

Longevity compound
NAD+
A central cellular coenzyme involved in energy metabolism, DNA repair and stress responses, studied because NAD biology changes with age.
6 healthy-aging outcome areas tracked
- Human research
50 outcome assessment(s) still require classification.
- Signal · Inflammation
- Safety
50 outcome assessment(s) still require classification.
2 result(s) are linked, but direction remains unknown.
Biomarker — does not establish a health benefit

Longevity compound
Nicotinamide riboside (NR)
A vitamin B3-derived NAD+ precursor being studied for effects on cellular energy metabolism and age-related physiology.
5 healthy-aging outcome areas tracked
- Human research
4 outcome assessment(s) still require classification.
- Signal · Inflammation
- Safety
4 outcome assessment(s) still require classification.
2 result(s) are linked, but direction remains unknown.
