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Physical function
VO₂max
Established risk / function markerCardiorespiratory fitnessExercise testmL/kg/min
A measure of maximal aerobic capacity.
What it measures
Maximum oxygen consumption during graded exercise.
Why it matters
Cardiorespiratory fitness is strongly associated with functional health and long-term outcomes.
How to interpret it
Interpret by age, sex, protocol and whether the value is directly measured or estimated.
Important limitations
Not a molecular biomarker and association alone does not make it a surrogate endpoint for longevity.
Evidence status
Established risk / function marker
Strong physiological risk marker and functional measure; valuable for healthy-aging assessment.
Research & guidance
Original papers, validation studies, reviews and clinical guidance connected to this measurement.
For education and evidence exploration, not diagnosis or individualized medical advice.