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Metabolic

Uric acid

Clinical biomarkerMetaboliteBloodµmol/L

The circulating end product of purine metabolism.

What it measures

Serum urate concentration.

Why it matters

Clinically central to gout and studied in cardiometabolic and renal disease.

How to interpret it

Interpret with symptoms, kidney function, diet and medications.

Important limitations

Associations with broader outcomes are confounded and do not make urate a general longevity target.

Evidence status

Clinical biomarker

Established disease-specific biomarker; broader longevity meaning is uncertain.

Research & guidance

Original papers, validation studies, reviews and clinical guidance connected to this measurement.

For education and evidence exploration, not diagnosis or individualized medical advice.