← All biomarkers
Biological aging
GrimAge / GrimAge2
Research-stage biomarkerEpigenetic clockBloodyears / acceleration
A DNA-methylation-derived predictor trained partly on mortality-related signals.
What it measures
Methylation surrogates and age/sex information combined into a mortality-oriented clock.
Why it matters
Shows mortality and healthspan associations across cohorts.
How to interpret it
Use the specific validated version and distinguish age estimate from age acceleration.
Important limitations
Predictive performance does not establish causal mechanisms or surrogate-endpoint validity.
Evidence status
Research-stage biomarker
Among better-validated mortality-oriented epigenetic clocks, but clinical utility remains under evaluation.
Research & guidance
Original papers, validation studies, reviews and clinical guidance connected to this measurement.
For education and evidence exploration, not diagnosis or individualized medical advice.