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Biological aging
DunedinPACE
Research-stage biomarkerEpigenetic pace-of-agingBloodrelative pace
A DNA-methylation measure designed to estimate pace of aging.
What it measures
Methylation signature trained against longitudinal change in multiple physiological systems.
Why it matters
Associated with aging-related outcomes and used in geroscience research.
How to interpret it
Interpret as a research measure with attention to population and assay reproducibility.
Important limitations
It is not established that changing the score itself causes improved health or longevity.
Evidence status
Research-stage biomarker
Promising pace-of-aging biomarker requiring further intervention and clinical validation.
Research & guidance
Original papers, validation studies, reviews and clinical guidance connected to this measurement.
For education and evidence exploration, not diagnosis or individualized medical advice.